Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-13
 13.0 74
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-13
 14.0 67
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-13
 12.0 82
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-13
 13.0 76
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-13
 14.0 67
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-13
 13.0 55
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL-13
 17.5 72
RA2159 Poly(I:C) 2
ug/mL
 2
IL-13
 17.0 57
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL-13
 14.0 58
N2645 Poly(I:C) 2
ug/mL
 2
IL-13
 18.0 69
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL-13
 16.0 77
RA2708 Poly(I:C) 2
ug/mL
 2
IL-13
 19.0 61
RA2159 5z-7-oxozeaenol 0.6
uM
 2
IL-13
 16.0 58
RA2159 IKK16 2.0
uM
 2
IL-13
 14.5 64
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL-13
 12.0 64
N2645 IKK16 2.0
uM
 2
IL-13
 14.0 90
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL-13
 13.0 69
RA2708 IKK16 2.0
uM
 2
IL-13
 12.0 62
RA2159 Tofacitinib 0.3
uM
 2
IL-13
 13.5 78
RA2159 2
IL-13
 16.0 64
N2645 Tofacitinib 0.3
uM
 2
IL-13
 14.5 62
N2645 2
IL-13
 15.5 46
RA2708 Tofacitinib 0.3
uM
 2
IL-13
 14.0 54
RA2708 2
IL-13
 14.0 51
0
IL-13
 11.0 52