Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IP-10
 15.0 65
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IP-10
 16.0 75
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IP-10
 16.5 52
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IP-10
 22.0 50
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IP-10
 13.0 52
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IP-10
 16.0 57
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IP-10
 499.5 46
RA2159 IL-1 alpha 100
ng/mL
 2
IP-10
 288.5 50
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IP-10
 659.5 50
N2645 IL-1 alpha 100
ng/mL
 2
IP-10
 1352.0 60
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IP-10
 412.0 69
RA2708 IL-1 alpha 100
ng/mL
 2
IP-10
 362.0 55
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IP-10
 71.0 49
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IP-10
 436.5 58
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IP-10
 17.0 68
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IP-10
 29.0 73
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IP-10
 23.0 50
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IP-10
 16.0 55
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IP-10
 4123.0 69
RA2159 Poly(I:C) 2
ug/mL
 2
IP-10
 6565.5 54
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IP-10
 2249.0 45
N2645 Poly(I:C) 2
ug/mL
 2
IP-10
 14590.5 40
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IP-10
 4617.0 65
RA2708 Poly(I:C) 2
ug/mL
 2
IP-10
 8264.0 49
RA2159 5z-7-oxozeaenol 0.6
uM
 2
IP-10
 14.0 48