Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 TNF-a 100
ng/mL
 1
MMP-2
 556.0 27
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MMP-2
 210.0 42
N2759 TNF-a 100
ng/mL
 1
MMP-2
 398.0 37
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MMP-2
 199.0 35
RA1931 TNF-a 100
ng/mL
 1
MMP-2
 207.5 18
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MMP-2
 304.0 50
N2586 TNF-a 100
ng/mL
 1
MMP-2
 356.0 44
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 363.0 31
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 592.0 19
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 484.0 42
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 454.0 35
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 229.0 37
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 151.5 40
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 634.5 38
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 279.0 39
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 305.0 36
RA1869 IL-1 alpha 100
ng/mL
 1
MMP-2
 649.0 41
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 253.0 27
N2759 IL-1 alpha 100
ng/mL
 1
MMP-2
 517.0 27
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 199.0 41
RA1931 IL-1 alpha 100
ng/mL
 1
MMP-2
 327.0 28
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 459.0 21
N2586 IL-1 alpha 100
ng/mL
 1
MMP-2
 358.0 43
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
MMP-2
 424.0 37
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
MMP-2
 471.0 31