Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
N2586 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 3 | M-CSF | 393.0 | 30 | |
N2586 | Poly(I:C) | 2 | ug/mL | 3 | M-CSF | 306.0 | 39 | ||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | M-CSF | 345.0 | 49 | |
RA1869 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | M-CSF | 357.0 | 46 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | M-CSF | 539.0 | 50 | |
N2759 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | M-CSF | 584.0 | 63 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | M-CSF | 423.0 | 59 | |
RA1931 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | M-CSF | 406.0 | 49 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | M-CSF | 516.0 | 54 | |
N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | M-CSF | 398.5 | 48 | |
RA1869 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | M-CSF | 648.0 | 42 | |
RA1869 | IL-1 alpha | 100 | ng/mL | 3 | M-CSF | 614.0 | 55 | ||||
N2759 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | M-CSF | 906.5 | 50 | |
N2759 | IL-1 alpha | 100 | ng/mL | 3 | M-CSF | 698.5 | 46 | ||||
RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | M-CSF | 710.0 | 42 | |
RA1931 | IL-1 alpha | 100 | ng/mL | 3 | M-CSF | 864.0 | 25 | ||||
N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | M-CSF | 594.0 | 38 | |
N2586 | IL-1 alpha | 100 | ng/mL | 3 | M-CSF | 453.0 | 41 | ||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | M-CSF | 389.0 | 43 | |
RA1869 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | M-CSF | 433.0 | 41 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | M-CSF | 828.0 | 43 | |
N2759 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | M-CSF | 730.5 | 50 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | M-CSF | 649.5 | 46 | |
RA1931 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | M-CSF | 491.0 | 31 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | M-CSF | 578.0 | 55 |