Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 5z-7-oxozeaenol 0.6
uM
1
M-CSF
568.5 48
N2759 IKK16 2.0
uM
1
M-CSF
575.0 44
RA1931 5z-7-oxozeaenol 0.6
uM
1
M-CSF
563.5 48
RA1931 IKK16 2.0
uM
1
M-CSF
558.0 47
N2586 5z-7-oxozeaenol 0.6
uM
1
M-CSF
556.5 32
N2586 IKK16 2.0
uM
1
M-CSF
440.0 40
RA1869 Tofacitinib 0.3
uM
1
M-CSF
426.5 52
RA1869 1
M-CSF
504.0 45
N2759 Tofacitinib 0.3
uM
1
M-CSF
619.0 53
N2759 1
M-CSF
676.0 59
RA1931 Tofacitinib 0.3
uM
1
M-CSF
525.0 31
RA1931 1
M-CSF
606.0 51
N2586 Tofacitinib 0.3
uM
1
M-CSF
426.0 30
N2586 1
M-CSF
361.0 35
RA1869 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
1
M-CSF
551.0 34
RA1869 IKK16 2.0
uM
TNF-a 100
ng/mL
1
M-CSF
599.5 50
N2759 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
1
M-CSF
931.0 54
N2759 IKK16 2.0
uM
TNF-a 100
ng/mL
1
M-CSF
817.0 55
RA1931 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
1
M-CSF
800.0 59
RA1931 IKK16 2.0
uM
TNF-a 100
ng/mL
1
M-CSF
578.0 60
N2586 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
1
M-CSF
735.0 45
N2586 IKK16 2.0
uM
TNF-a 100
ng/mL
1
M-CSF
664.0 59
RA1869 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
M-CSF
804.0 57
RA1869 TNF-a 100
ng/mL
1
M-CSF
757.5 58
N2759 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
M-CSF
1208.0 36