Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL3
 46.5 46
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL3
 40.5 40
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL3
 54.0 69
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL3
 45.0 47
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL3
 56.0 41
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL3
 50.0 40
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL3
 30.0 45
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL3
 51.5 46
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL3
 40.0 50
RA1869 TNF-a 100
ng/mL
 1
IL3
 49.0 57
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL3
 56.0 47
N2759 TNF-a 100
ng/mL
 1
IL3
 42.0 44
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL3
 52.5 46
RA1931 TNF-a 100
ng/mL
 1
IL3
 47.0 55
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL3
 50.5 28
N2586 TNF-a 100
ng/mL
 1
IL3
 44.5 38
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 87.0 40
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 78.0 49
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 76.0 53
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 93.5 54
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 81.0 41
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 85.0 50
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 82.0 50
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 76.0 51
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 78.5 36