Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL1-a | 29894.0 | 66 | |
RA1869 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL1-a | 31600.0 | 65 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL1-a | 32680.5 | 68 | |
N2759 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL1-a | 31213.0 | 72 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL1-a | 31235.5 | 68 | |
RA1931 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL1-a | 30303.0 | 64 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL1-a | 32191.5 | 64 | |
N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL1-a | 30417.0 | 63 | |
RA1869 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL1-a | 30667.0 | 71 | |
RA1869 | IL-1 alpha | 100 | ng/mL | 3 | IL1-a | 30496.5 | 60 | ||||
N2759 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL1-a | 30872.0 | 49 | |
N2759 | IL-1 alpha | 100 | ng/mL | 3 | IL1-a | 29734.5 | 56 | ||||
RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL1-a | 29666.0 | 58 | |
RA1931 | IL-1 alpha | 100 | ng/mL | 3 | IL1-a | 30212.0 | 47 | ||||
N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL1-a | 30303.0 | 59 | |
N2586 | IL-1 alpha | 100 | ng/mL | 3 | IL1-a | 30087.0 | 52 | ||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | IL1-a | 179.5 | 52 | |
RA1869 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL1-a | 215.0 | 60 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | IL1-a | 218.0 | 61 | |
N2759 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL1-a | 214.0 | 51 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | IL1-a | 195.5 | 58 | |
RA1931 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL1-a | 211.0 | 51 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | IL1-a | 173.0 | 67 | |
N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL1-a | 198.0 | 46 | |
RA1869 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | IL1-a | 206.0 | 63 |