Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL1-a
29894.0 66
RA1869 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL1-a
31600.0 65
N2759 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL1-a
32680.5 68
N2759 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL1-a
31213.0 72
RA1931 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL1-a
31235.5 68
RA1931 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL1-a
30303.0 64
N2586 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL1-a
32191.5 64
N2586 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL1-a
30417.0 63
RA1869 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
3
IL1-a
30667.0 71
RA1869 IL-1 alpha 100
ng/mL
3
IL1-a
30496.5 60
N2759 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
3
IL1-a
30872.0 49
N2759 IL-1 alpha 100
ng/mL
3
IL1-a
29734.5 56
RA1931 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
3
IL1-a
29666.0 58
RA1931 IL-1 alpha 100
ng/mL
3
IL1-a
30212.0 47
N2586 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
3
IL1-a
30303.0 59
N2586 IL-1 alpha 100
ng/mL
3
IL1-a
30087.0 52
RA1869 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
3
IL1-a
179.5 52
RA1869 IKK16 2.0
uM
TNF-a 100
ng/mL
3
IL1-a
215.0 60
N2759 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
3
IL1-a
218.0 61
N2759 IKK16 2.0
uM
TNF-a 100
ng/mL
3
IL1-a
214.0 51
RA1931 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
3
IL1-a
195.5 58
RA1931 IKK16 2.0
uM
TNF-a 100
ng/mL
3
IL1-a
211.0 51
N2586 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
3
IL1-a
173.0 67
N2586 IKK16 2.0
uM
TNF-a 100
ng/mL
3
IL1-a
198.0 46
RA1869 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
3
IL1-a
206.0 63