Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 TNF-a 100
ng/mL
 2
IL1-a
 280.0 49
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 32101.5 58
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 32958.0 57
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 33301.0 63
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 33369.0 61
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 33438.0 49
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 32867.0 48
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 33712.0 71
RA2159 IL-1 alpha 100
ng/mL
 2
IL1-a
 33186.5 44
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 32912.5 44
N2645 IL-1 alpha 100
ng/mL
 2
IL1-a
 33758.0 43
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL1-a
 33895.0 43
RA2708 IL-1 alpha 100
ng/mL
 2
IL1-a
 33917.0 47
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL1-a
 283.5 60
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL1-a
 341.0 55
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL1-a
 287.0 43
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL1-a
 306.0 58
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL1-a
 323.0 38
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL1-a
 307.5 42
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL1-a
 230.5 50
RA2159 Poly(I:C) 2
ug/mL
 2
IL1-a
 298.0 61
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL1-a
 237.5 58
N2645 Poly(I:C) 2
ug/mL
 2
IL1-a
 309.5 40
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL1-a
 276.0 56
RA2708 Poly(I:C) 2
ug/mL
 2
IL1-a
 184.0 38