Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
RA1869 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | GRO-a | 8854.0 | 50 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | GRO-a | 1741.5 | 62 | |
N2759 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | GRO-a | 15488.5 | 56 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | GRO-a | 393.0 | 45 | |
RA1931 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | GRO-a | 14348.0 | 53 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | GRO-a | 959.0 | 42 | |
N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | GRO-a | 12814.0 | 64 | |
RA1869 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | GRO-a | 18552.5 | 52 | |
RA1869 | IL-1 alpha | 100 | ng/mL | 3 | GRO-a | 18461.5 | 64 | ||||
N2759 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | GRO-a | 18746.0 | 61 | |
N2759 | IL-1 alpha | 100 | ng/mL | 3 | GRO-a | 18655.0 | 41 | ||||
RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | GRO-a | 19156.0 | 55 | |
RA1931 | IL-1 alpha | 100 | ng/mL | 3 | GRO-a | 18552.5 | 44 | ||||
N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | GRO-a | 18678.0 | 61 | |
N2586 | IL-1 alpha | 100 | ng/mL | 3 | GRO-a | 17791.0 | 56 | ||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | GRO-a | 144.0 | 46 | |
RA1869 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | GRO-a | 2915.0 | 51 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | GRO-a | 1196.5 | 52 | |
N2759 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | GRO-a | 5640.0 | 56 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | GRO-a | 2121.0 | 52 | |
RA1931 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | GRO-a | 5617.5 | 50 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | GRO-a | 2099.0 | 41 | |
N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | GRO-a | 6765.5 | 60 | |
RA1869 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | GRO-a | 8026.0 | 61 | |
RA1869 | TNF-a | 100 | ng/mL | 3 | GRO-a | 7275.5 | 54 |