Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 35.0 65
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 36.0 68
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 38.5 58
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 42.0 49
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 39.5 56
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 39.0 60
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 41.0 59
RA1869 IL-1 alpha 100
ng/mL
 3
IL18
 45.5 46
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 41.0 53
N2759 IL-1 alpha 100
ng/mL
 3
IL18
 36.0 49
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 40.0 64
RA1931 IL-1 alpha 100
ng/mL
 3
IL18
 46.0 46
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 45.5 46
N2586 IL-1 alpha 100
ng/mL
 3
IL18
 40.0 52
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL18
 21.0 49
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL18
 18.0 61
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL18
 15.5 52
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL18
 19.0 56
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL18
 19.0 62
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL18
 24.0 44
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL18
 18.0 63
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL18
 19.0 62
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL18
 18.0 50
RA1869 TNF-a 100
ng/mL
 3
IL18
 21.0 67
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL18
 19.0 52