Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 IKK16 2.0
uM
TNF-a 100
ng/mL
1
MIF
111.5 60
RA1931 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
1
MIF
99.0 67
RA1931 IKK16 2.0
uM
TNF-a 100
ng/mL
1
MIF
61.0 63
N2586 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
1
MIF
183.0 63
N2586 IKK16 2.0
uM
TNF-a 100
ng/mL
1
MIF
164.0 65
RA1869 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
MIF
34.0 64
RA1869 TNF-a 100
ng/mL
1
MIF
32.0 69
N2759 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
MIF
27.0 51
N2759 TNF-a 100
ng/mL
1
MIF
27.5 64
RA1931 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
MIF
30.0 69
RA1931 TNF-a 100
ng/mL
1
MIF
28.0 51
N2586 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
MIF
29.0 36
N2586 TNF-a 100
ng/mL
1
MIF
27.5 62
RA1869 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
1
MIF
50.0 47
RA1869 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
MIF
48.5 64
N2759 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
1
MIF
36.5 80
N2759 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
MIF
44.0 56
RA1931 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
1
MIF
39.0 59
RA1931 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
MIF
39.0 53
N2586 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
1
MIF
38.0 69
N2586 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
MIF
39.0 61
RA1869 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
1
MIF
44.0 63
RA1869 IL-1 alpha 100
ng/mL
1
MIF
57.0 54
N2759 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
1
MIF
35.0 55
N2759 IL-1 alpha 100
ng/mL
1
MIF
35.0 68