Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-1RA
 48.0 57
N2759 Poly(I:C) 2
ug/mL
 3
IL-1RA
 50.5 58
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-1RA
 52.0 61
RA1931 Poly(I:C) 2
ug/mL
 3
IL-1RA
 62.0 47
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-1RA
 64.0 63
N2586 Poly(I:C) 2
ug/mL
 3
IL-1RA
 61.5 48
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 21.0 55
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 31.0 64
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 19.5 50
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 29.0 55
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 21.0 62
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 32.0 65
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 22.0 84
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 27.5 62
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 71.0 50
RA1869 IL-1 alpha 100
ng/mL
 3
IL-1RA
 85.0 61
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 84.0 48
N2759 IL-1 alpha 100
ng/mL
 3
IL-1RA
 94.0 61
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 83.5 46
RA1931 IL-1 alpha 100
ng/mL
 3
IL-1RA
 92.5 62
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 75.0 63
N2586 IL-1 alpha 100
ng/mL
 3
IL-1RA
 79.5 48
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 94.0 59
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 108.0 66
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 78.5 54