Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 96.0 51
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 89.0 46
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 97.0 51
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 91.0 35
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 86.5 62
RA2159 IL-1 alpha 100
ng/mL
 2
TNFb
 86.0 30
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 84.0 39
N2645 IL-1 alpha 100
ng/mL
 2
TNFb
 84.0 41
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 92.0 43
RA2708 IL-1 alpha 100
ng/mL
 2
TNFb
 79.0 44
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
TNFb
 37.0 59
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
TNFb
 36.5 46
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
TNFb
 42.5 46
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
TNFb
 51.0 55
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
TNFb
 39.5 52
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
TNFb
 45.0 41
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
TNFb
 39.0 50
RA2159 Poly(I:C) 2
ug/mL
 2
TNFb
 43.0 47
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
TNFb
 47.0 43
N2645 Poly(I:C) 2
ug/mL
 2
TNFb
 36.0 37
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
TNFb
 35.0 41
RA2708 Poly(I:C) 2
ug/mL
 2
TNFb
 48.0 32
RA2159 5z-7-oxozeaenol 0.6
uM
 2
TNFb
 38.0 51
RA2159 IKK16 2.0
uM
 2
TNFb
 36.5 60
N2645 5z-7-oxozeaenol 0.6
uM
 2
TNFb
 35.0 47