Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
LIF
 132.0 57
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
LIF
 135.0 60
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
LIF
 140.0 59
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
LIF
 187.0 40
RA2159 IL-1 alpha 100
ng/mL
 4
LIF
 194.0 40
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
LIF
 178.5 36
N2645 IL-1 alpha 100
ng/mL
 4
LIF
 182.0 49
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
LIF
 212.0 35
RA2708 IL-1 alpha 100
ng/mL
 4
LIF
 221.0 26
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
LIF
 43.5 50
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
LIF
 51.0 36
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
LIF
 50.0 50
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
LIF
 51.5 48
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
LIF
 41.0 47
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
LIF
 61.0 48
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
LIF
 68.0 45
RA2159 TNF-a 100
ng/mL
 4
LIF
 64.0 39
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
LIF
 76.0 49
N2645 TNF-a 100
ng/mL
 4
LIF
 95.0 50
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
LIF
 64.0 39
RA2708 TNF-a 100
ng/mL
 4
LIF
 65.0 39
RA2159 5z-7-oxozeaenol 0.6
uM
 4
LIF
 50.0 33
RA2159 IKK16 2.0
uM
 4
LIF
 49.0 31
N2645 5z-7-oxozeaenol 0.6
uM
 4
LIF
 44.0 47
N2645 IKK16 2.0
uM
 4
LIF
 42.5 34