Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
LIF
 47.0 43
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
LIF
 41.0 29
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
LIF
 42.0 49
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
LIF
 48.0 45
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
LIF
 49.0 31
RA2159 TNF-a 100
ng/mL
 2
LIF
 45.0 32
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
LIF
 70.5 30
N2645 TNF-a 100
ng/mL
 2
LIF
 49.5 38
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
LIF
 52.0 33
RA2708 TNF-a 100
ng/mL
 2
LIF
 61.0 29
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
LIF
 111.0 39
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
LIF
 105.0 42
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
LIF
 111.0 33
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
LIF
 122.0 36
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
LIF
 103.0 31
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
LIF
 118.0 25
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
LIF
 140.0 45
RA2159 IL-1 alpha 100
ng/mL
 2
LIF
 140.0 32
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
LIF
 125.5 44
N2645 IL-1 alpha 100
ng/mL
 2
LIF
 121.0 39
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
LIF
 152.0 37
RA2708 IL-1 alpha 100
ng/mL
 2
LIF
 150.0 41
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
LIF
 39.5 38
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
LIF
 34.0 25
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
LIF
 40.0 39