Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 5z-7-oxozeaenol 0.6
uM
2
IL12(p40)
141.0 39
N2645 IKK16 2.0
uM
2
IL12(p40)
199.5 62
RA2708 5z-7-oxozeaenol 0.6
uM
2
IL12(p40)
170.0 47
RA2708 IKK16 2.0
uM
2
IL12(p40)
208.0 42
RA2159 Tofacitinib 0.3
uM
2
IL12(p40)
155.0 51
RA2159 2
IL12(p40)
163.0 73
N2645 Tofacitinib 0.3
uM
2
IL12(p40)
181.0 73
N2645 2
IL12(p40)
187.0 62
RA2708 Tofacitinib 0.3
uM
2
IL12(p40)
177.0 58
RA2708 2
IL12(p40)
172.0 48
RA2159 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
2
IL12(p40)
162.0 75
RA2159 IKK16 2.0
uM
TNF-a 100
ng/mL
2
IL12(p40)
161.5 72
N2645 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
2
IL12(p40)
159.0 51
N2645 IKK16 2.0
uM
TNF-a 100
ng/mL
2
IL12(p40)
198.0 62
RA2708 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
2
IL12(p40)
196.0 59
RA2708 IKK16 2.0
uM
TNF-a 100
ng/mL
2
IL12(p40)
142.0 49
RA2159 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
2
IL12(p40)
150.5 54
RA2159 TNF-a 100
ng/mL
2
IL12(p40)
161.0 41
N2645 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
2
IL12(p40)
177.0 59
N2645 TNF-a 100
ng/mL
2
IL12(p40)
146.5 56
RA2708 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
2
IL12(p40)
173.0 25
RA2708 TNF-a 100
ng/mL
2
IL12(p40)
204.0 45
RA2159 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
2
IL12(p40)
154.0 61
RA2159 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
2
IL12(p40)
192.0 52
N2645 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
2
IL12(p40)
209.0 66