Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 121.5 52
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 183.0 45
RA1869 TNF-a 100
ng/mL
 1
IL-1RA
 190.0 47
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 132.0 82
N2759 TNF-a 100
ng/mL
 1
IL-1RA
 153.0 62
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 180.0 58
RA1931 TNF-a 100
ng/mL
 1
IL-1RA
 196.0 44
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 145.0 57
N2586 TNF-a 100
ng/mL
 1
IL-1RA
 147.0 51
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 25.0 56
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 32.0 37
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 26.0 55
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 30.0 45
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 23.0 57
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 34.5 42
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 28.0 47
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 31.0 59
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 84.5 62
RA1869 IL-1 alpha 100
ng/mL
 1
IL-1RA
 95.0 43
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 78.5 64
N2759 IL-1 alpha 100
ng/mL
 1
IL-1RA
 93.5 44
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 83.0 59
RA1931 IL-1 alpha 100
ng/mL
 1
IL-1RA
 87.5 44
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 103.0 51
N2586 IL-1 alpha 100
ng/mL
 1
IL-1RA
 97.0 51