Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
MCP3
 19.0 82
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
MCP3
 21.0 63
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
MCP3
 31.0 87
RA2159 Poly(I:C) 2
ug/mL
 4
MCP3
 44.5 88
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
MCP3
 19.0 71
N2645 Poly(I:C) 2
ug/mL
 4
MCP3
 20.0 69
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
MCP3
 35.0 66
RA2708 Poly(I:C) 2
ug/mL
 4
MCP3
 41.5 76
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
MCP3
 27.0 87
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
MCP3
 25.0 75
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
MCP3
 29.0 84
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
MCP3
 25.0 77
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
MCP3
 24.0 77
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
MCP3
 35.0 77
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
MCP3
 114.0 84
RA2159 IL-1 alpha 100
ng/mL
 4
MCP3
 111.0 67
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
MCP3
 33.0 65
N2645 IL-1 alpha 100
ng/mL
 4
MCP3
 35.5 72
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
MCP3
 87.0 73
RA2708 IL-1 alpha 100
ng/mL
 4
MCP3
 105.0 46
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
MCP3
 21.0 77
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
MCP3
 30.0 68
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
MCP3
 18.0 87
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
MCP3
 15.0 73
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
MCP3
 21.0 83