Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 IKK16 2.0
uM
 2
MCP3
 19.0 59
RA2708 5z-7-oxozeaenol 0.6
uM
 2
MCP3
 20.0 68
RA2708 IKK16 2.0
uM
 2
MCP3
 20.0 66
RA2159 Tofacitinib 0.3
uM
 2
MCP3
 20.0 52
RA2159 2
MCP3
 19.0 73
N2645 Tofacitinib 0.3
uM
 2
MCP3
 21.5 50
N2645 2
MCP3
 19.0 67
RA2708 Tofacitinib 0.3
uM
 2
MCP3
 19.0 56
RA2708 2
MCP3
 19.0 52
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MCP3
 17.0 68
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MCP3
 27.0 71
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MCP3
 20.0 77
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MCP3
 17.0 73
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MCP3
 21.0 59
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MCP3
 23.0 67
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MCP3
 29.0 51
RA2159 TNF-a 100
ng/mL
 2
MCP3
 31.0 72
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MCP3
 21.0 43
N2645 TNF-a 100
ng/mL
 2
MCP3
 20.0 58
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MCP3
 28.5 48
RA2708 TNF-a 100
ng/mL
 2
MCP3
 30.0 27
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MCP3
 21.0 76
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MCP3
 27.0 72
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MCP3
 21.0 64
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MCP3
 23.0 61