Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL2-Ra
 26.0 61
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL2-Ra
 27.0 79
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL2-Ra
 22.5 66
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL2-Ra
 28.0 51
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL2-Ra
 24.0 58
RA1869 IL-1 alpha 100
ng/mL
 1
IL2-Ra
 27.0 43
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL2-Ra
 26.0 67
N2759 IL-1 alpha 100
ng/mL
 1
IL2-Ra
 28.0 49
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL2-Ra
 33.0 41
RA1931 IL-1 alpha 100
ng/mL
 1
IL2-Ra
 29.5 66
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL2-Ra
 28.0 42
N2586 IL-1 alpha 100
ng/mL
 1
IL2-Ra
 25.5 44
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL2-Ra
 19.0 37
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL2-Ra
 14.0 50
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL2-Ra
 19.0 62
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL2-Ra
 14.0 66
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL2-Ra
 19.0 70
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL2-Ra
 19.0 47
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL2-Ra
 16.0 61
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL2-Ra
 17.0 53
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL2-Ra
 15.0 54
RA1869 Poly(I:C) 2
ug/mL
 1
IL2-Ra
 12.5 38
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL2-Ra
 16.0 71
N2759 Poly(I:C) 2
ug/mL
 1
IL2-Ra
 17.0 70
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL2-Ra
 28.0 59