Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 JNK-IN-8 3.0
uM
 3
IL-17
 34.0 43
N2586 PH-797804 0.6
uM
 3
IL-17
 31.5 44
RA1869 Poly(I:C) 2
ug/mL
 3
IL-17
 39.5 64
N2759 Poly(I:C) 2
ug/mL
 3
IL-17
 67.5 58
RA1931 Poly(I:C) 2
ug/mL
 3
IL-17
 67.0 49
N2586 Poly(I:C) 2
ug/mL
 3
IL-17
 74.0 58
RA1869 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-17
 32.0 53
RA1869 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-17
 52.5 58
N2759 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-17
 37.0 54
N2759 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-17
 47.0 58
RA1931 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-17
 44.0 39
RA1931 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-17
 48.0 49
N2586 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-17
 40.0 56
N2586 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-17
 49.0 43
RA1869 IL-1 alpha 100
ng/mL
 3
IL-17
 70.0 69
N2759 IL-1 alpha 100
ng/mL
 3
IL-17
 72.0 50
RA1931 IL-1 alpha 100
ng/mL
 3
IL-17
 72.5 64
N2586 IL-1 alpha 100
ng/mL
 3
IL-17
 63.0 61
RA1869 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-17
 59.0 59
RA1869 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-17
 57.5 52
N2759 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-17
 72.0 57
N2759 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-17
 66.0 71
RA1931 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-17
 75.0 37
RA1931 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-17
 69.0 56
N2586 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-17
 77.5 68