Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA1931 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 79.0 | 70 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 52.5 | 62 | |
| N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 83.5 | 68 | |
| RA1869 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 95.0 | 63 | |
| RA1869 | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 112.5 | 60 | ||||
| N2759 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 58.0 | 53 | |
| N2759 | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 57.5 | 62 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 101.0 | 58 | |
| RA1931 | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 109.0 | 63 | ||||
| N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 76.0 | 47 | |
| N2586 | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 76.0 | 59 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | 3 | IL-12 (p70) | 53.0 | 41 | ||||
| RA1869 | IKK16 | 2.0 | uM | 3 | IL-12 (p70) | 81.0 | 45 | ||||
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | 3 | IL-12 (p70) | 39.0 | 53 | ||||
| N2759 | IKK16 | 2.0 | uM | 3 | IL-12 (p70) | 43.0 | 60 | ||||
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | 3 | IL-12 (p70) | 60.0 | 55 | ||||
| RA1931 | IKK16 | 2.0 | uM | 3 | IL-12 (p70) | 81.5 | 68 | ||||
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | 3 | IL-12 (p70) | 53.5 | 60 | ||||
| N2586 | IKK16 | 2.0 | uM | 3 | IL-12 (p70) | 66.5 | 42 | ||||
| RA1869 | Tofacitinib | 0.3 | uM | 3 | IL-12 (p70) | 81.5 | 52 | ||||
| RA1869 | 3 | IL-12 (p70) | 107.0 | 47 | |||||||
| N2759 | Tofacitinib | 0.3 | uM | 3 | IL-12 (p70) | 52.0 | 49 | ||||
| N2759 | 3 | IL-12 (p70) | 58.0 | 53 | |||||||
| RA1931 | Tofacitinib | 0.3 | uM | 3 | IL-12 (p70) | 90.0 | 57 | ||||
| RA1931 | 3 | IL-12 (p70) | 85.0 | 78 |