Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 34.0 51
N2645 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 45.0 43
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 51.0 42
RA2708 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 51.0 43
RA2159 5z-7-oxozeaenol 0.6
uM
 2
IL-12 (p70)
 40.5 50
RA2159 IKK16 2.0
uM
 2
IL-12 (p70)
 44.0 66
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL-12 (p70)
 37.0 53
N2645 IKK16 2.0
uM
 2
IL-12 (p70)
 34.0 60
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL-12 (p70)
 38.5 54
RA2708 IKK16 2.0
uM
 2
IL-12 (p70)
 48.0 55
RA2159 Tofacitinib 0.3
uM
 2
IL-12 (p70)
 46.0 61
RA2159 2
IL-12 (p70)
 55.5 48
N2645 Tofacitinib 0.3
uM
 2
IL-12 (p70)
 34.0 44
N2645 2
IL-12 (p70)
 35.5 54
RA2708 Tofacitinib 0.3
uM
 2
IL-12 (p70)
 57.0 51
RA2708 2
IL-12 (p70)
 46.5 28
0
IL-12 (p70)
 20.0 52
0
IL-12 (p70)
 19.0 42
0
IL-12 (p70)
 18.5 42
0
IL-12 (p70)
 18.0 46
0
IL-12 (p70)
 17.0 57
0
IL-12 (p70)
 13.0 27
RA1869 5z-7-oxozeaenol 0.6
uM
 3
IL-12 (p70)
 61.0 50
RA1869 IKK16 2.0
uM
 3
IL-12 (p70)
 86.0 45
N2759 5z-7-oxozeaenol 0.6
uM
 3
IL-12 (p70)
 52.0 50