Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 Poly(I:C) 2
ug/mL
 4
G-CSF
 34.5 32
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
G-CSF
 147.5 32
RA2708 Poly(I:C) 2
ug/mL
 4
G-CSF
 146.0 22
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
G-CSF
 14.0 47
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
G-CSF
 29.0 43
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
G-CSF
 18.0 53
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
G-CSF
 26.0 51
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
G-CSF
 19.0 48
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
G-CSF
 80.5 38
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
G-CSF
 885.0 36
RA2159 IL-1 alpha 100
ng/mL
 4
G-CSF
 663.5 32
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
G-CSF
 59.0 36
N2645 IL-1 alpha 100
ng/mL
 4
G-CSF
 74.0 34
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
G-CSF
 1090.0 21
RA2708 IL-1 alpha 100
ng/mL
 4
G-CSF
 905.5 36
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
G-CSF
 55.0 56
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
G-CSF
 57.0 36
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
G-CSF
 37.0 48
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
G-CSF
 41.5 36
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
G-CSF
 47.0 51
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
G-CSF
 35.0 39
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
G-CSF
 65.0 25
RA2159 TNF-a 100
ng/mL
 4
G-CSF
 82.5 34
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
G-CSF
 62.0 41
N2645 TNF-a 100
ng/mL
 4
G-CSF
 69.0 26