Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
N2759 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | G-CSF | 936.0 | 85 | |
N2759 | IL-1 alpha | 100 | ng/mL | 3 | G-CSF | 1094.0 | 61 | ||||
RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | G-CSF | 372.5 | 80 | |
RA1931 | IL-1 alpha | 100 | ng/mL | 3 | G-CSF | 663.0 | 66 | ||||
N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | G-CSF | 480.5 | 52 | |
N2586 | IL-1 alpha | 100 | ng/mL | 3 | G-CSF | 501.0 | 74 | ||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | G-CSF | 43.0 | 61 | |
RA1869 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | G-CSF | 53.5 | 62 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | G-CSF | 36.0 | 69 | |
N2759 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | G-CSF | 38.0 | 81 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | G-CSF | 34.0 | 67 | |
RA1931 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | G-CSF | 42.0 | 62 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | G-CSF | 44.5 | 64 | |
N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | G-CSF | 48.5 | 76 | |
RA1869 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | G-CSF | 65.0 | 81 | |
RA1869 | TNF-a | 100 | ng/mL | 3 | G-CSF | 78.0 | 49 | ||||
N2759 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | G-CSF | 50.0 | 81 | |
N2759 | TNF-a | 100 | ng/mL | 3 | G-CSF | 52.0 | 75 | ||||
RA1931 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | G-CSF | 54.0 | 55 | |
RA1931 | TNF-a | 100 | ng/mL | 3 | G-CSF | 67.0 | 48 | ||||
N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | G-CSF | 57.0 | 67 | |
N2586 | TNF-a | 100 | ng/mL | 3 | G-CSF | 62.0 | 69 | ||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | 3 | G-CSF | 15.5 | 44 | ||||
RA1869 | IKK16 | 2.0 | uM | 3 | G-CSF | 18.0 | 51 | ||||
N2759 | 5z-7-oxozeaenol | 0.6 | uM | 3 | G-CSF | 19.0 | 79 |