Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2708 | Poly(I:C) | 2 | ug/mL | 4 | MCP-1 (MCAF) | 5609.5 | 30 | ||||
| RA2159 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 4 | MCP-1 (MCAF) | 59.5 | 26 | |
| RA2159 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | MCP-1 (MCAF) | 472.0 | 26 | |
| N2645 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 4 | MCP-1 (MCAF) | 265.0 | 32 | |
| N2645 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | MCP-1 (MCAF) | 1265.0 | 32 | |
| RA2708 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 4 | MCP-1 (MCAF) | 98.0 | 27 | |
| RA2708 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | MCP-1 (MCAF) | 1337.0 | 29 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 4 | MCP-1 (MCAF) | 6303.0 | 29 | |
| RA2159 | IL-1 alpha | 100 | ng/mL | 4 | MCP-1 (MCAF) | 6586.0 | 28 | ||||
| N2645 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 4 | MCP-1 (MCAF) | 5566.5 | 22 | |
| N2645 | IL-1 alpha | 100 | ng/mL | 4 | MCP-1 (MCAF) | 6488.0 | 28 | ||||
| RA2708 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 4 | MCP-1 (MCAF) | 6352.0 | 21 | |
| RA2708 | IL-1 alpha | 100 | ng/mL | 4 | MCP-1 (MCAF) | 5181.5 | 24 | ||||
| RA2159 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 4 | MCP-1 (MCAF) | 687.0 | 29 | |
| RA2159 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 4 | MCP-1 (MCAF) | 3354.0 | 31 | |
| N2645 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 4 | MCP-1 (MCAF) | 169.0 | 39 | |
| N2645 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 4 | MCP-1 (MCAF) | 1412.0 | 19 | |
| RA2708 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 4 | MCP-1 (MCAF) | 520.0 | 27 | |
| RA2708 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 4 | MCP-1 (MCAF) | 1728.5 | 36 | |
| RA2159 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 4 | MCP-1 (MCAF) | 6603.0 | 29 | |
| RA2159 | TNF-a | 100 | ng/mL | 4 | MCP-1 (MCAF) | 7561.0 | 27 | ||||
| N2645 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 4 | MCP-1 (MCAF) | 6611.0 | 17 | |
| N2645 | TNF-a | 100 | ng/mL | 4 | MCP-1 (MCAF) | 7695.0 | 25 | ||||
| RA2708 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 4 | MCP-1 (MCAF) | 4143.5 | 28 | |
| RA2708 | TNF-a | 100 | ng/mL | 4 | MCP-1 (MCAF) | 5399.0 | 23 |