Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | MCP-1 (MCAF) | 7657.0 | 41 | |
| RA1931 | IL-1 alpha | 100 | ng/mL | 3 | MCP-1 (MCAF) | 8177.0 | 57 | ||||
| N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | MCP-1 (MCAF) | 6920.5 | 52 | |
| N2586 | IL-1 alpha | 100 | ng/mL | 3 | MCP-1 (MCAF) | 6077.0 | 37 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 1616.0 | 43 | |
| RA1869 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 4379.0 | 43 | |
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 200.0 | 35 | |
| N2759 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 551.0 | 52 | |
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 1376.0 | 57 | |
| RA1931 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 1842.0 | 51 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 677.0 | 56 | |
| N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 2444.0 | 50 | |
| RA1869 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 7670.0 | 47 | |
| RA1869 | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 8169.0 | 50 | ||||
| N2759 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 6626.5 | 46 | |
| N2759 | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 7059.5 | 44 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 7160.0 | 48 | |
| RA1931 | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 6680.0 | 49 | ||||
| N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 6594.0 | 35 | |
| N2586 | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 7408.0 | 53 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | 3 | MCP-1 (MCAF) | 81.0 | 45 | ||||
| RA1869 | IKK16 | 2.0 | uM | 3 | MCP-1 (MCAF) | 173.0 | 47 | ||||
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | 3 | MCP-1 (MCAF) | 46.0 | 39 | ||||
| N2759 | IKK16 | 2.0 | uM | 3 | MCP-1 (MCAF) | 51.0 | 57 | ||||
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | 3 | MCP-1 (MCAF) | 71.5 | 50 |