Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA1869 | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 7731.0 | 37 | ||||
| N2759 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 6648.0 | 39 | |
| N2759 | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 6971.0 | 61 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 7297.0 | 52 | |
| RA1931 | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 7855.0 | 41 | ||||
| N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 7445.0 | 27 | |
| N2586 | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 6379.0 | 52 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 76.5 | 36 | |
| RA1869 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 244.5 | 38 | |
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 143.5 | 50 | |
| N2759 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 136.5 | 40 | |
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 292.0 | 50 | |
| RA1931 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 400.0 | 49 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 260.0 | 43 | |
| N2586 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 311.0 | 40 | |
| RA1869 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 5886.0 | 46 | |
| RA1869 | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 7204.0 | 31 | ||||
| N2759 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 4601.5 | 62 | |
| N2759 | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 5942.0 | 47 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 5387.0 | 51 | |
| RA1931 | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 7018.0 | 53 | ||||
| N2586 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 4980.0 | 42 | |
| N2586 | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 5945.0 | 45 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | 1 | MCP-1 (MCAF) | 59.0 | 47 | ||||
| RA1869 | IKK16 | 2.0 | uM | 1 | MCP-1 (MCAF) | 80.0 | 39 |