Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 4
IL-4
 18.0 14
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-4
 24.0 39
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-4
 39.0 23
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-4
 23.0 43
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-4
 31.0 34
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-4
 21.0 25
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-4
 33.0 41
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL-4
 52.0 29
RA2159 Poly(I:C) 2
ug/mL
 4
IL-4
 64.0 23
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL-4
 25.0 27
N2645 Poly(I:C) 2
ug/mL
 4
IL-4
 36.5 38
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL-4
 76.0 27
RA2708 Poly(I:C) 2
ug/mL
 4
IL-4
 76.0 19
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-4
 19.0 29
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-4
 28.0 37
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-4
 21.0 46
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-4
 30.5 30
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-4
 17.5 30
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-4
 41.0 23
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-4
 80.5 36
RA2159 IL-1 alpha 100
ng/mL
 4
IL-4
 83.0 32
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-4
 52.0 29
N2645 IL-1 alpha 100
ng/mL
 4
IL-4
 50.0 19
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-4
 85.0 25
RA2708 IL-1 alpha 100
ng/mL
 4
IL-4
 74.5 28