Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 2
IL-13
 13.0 53
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-13
 16.5 80
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-13
 18.5 58
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-13
 15.0 51
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-13
 15.0 51
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-13
 17.0 52
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-13
 17.0 58
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-13
 18.0 63
RA2159 TNF-a 100
ng/mL
 2
IL-13
 15.0 51
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-13
 22.0 32
N2645 TNF-a 100
ng/mL
 2
IL-13
 14.0 44
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-13
 19.5 46
RA2708 TNF-a 100
ng/mL
 2
IL-13
 20.0 51
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-13
 15.0 59
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-13
 17.5 52
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-13
 13.0 54
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-13
 16.0 65
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-13
 11.0 55
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-13
 18.5 56
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-13
 16.0 59
RA2159 IL-1 alpha 100
ng/mL
 2
IL-13
 21.0 61
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-13
 17.0 43
N2645 IL-1 alpha 100
ng/mL
 2
IL-13
 18.0 43
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-13
 17.0 49
RA2708 IL-1 alpha 100
ng/mL
 2
IL-13
 15.5 46