Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 5z-7-oxozeaenol 0.6
uM
 3
IL-6
 1083.0 73
N2759 IKK16 2.0
uM
 3
IL-6
 1197.5 80
RA1931 5z-7-oxozeaenol 0.6
uM
 3
IL-6
 3214.0 59
RA1931 IKK16 2.0
uM
 3
IL-6
 2796.0 90
N2586 5z-7-oxozeaenol 0.6
uM
 3
IL-6
 3594.0 73
N2586 IKK16 2.0
uM
 3
IL-6
 5323.5 88
RA1869 Tofacitinib 0.3
uM
 3
IL-6
 3119.0 75
RA1869 3
IL-6
 3951.0 83
N2759 Tofacitinib 0.3
uM
 3
IL-6
 1120.5 92
N2759 3
IL-6
 1105.0 97
RA1931 Tofacitinib 0.3
uM
 3
IL-6
 4203.0 69
RA1931 3
IL-6
 3349.5 66
N2586 Tofacitinib 0.3
uM
 3
IL-6
 3859.0 77
N2586 3
IL-6
 5270.0 49
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-6
 1911.0 61
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-6
 6421.5 96
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-6
 1063.0 62
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-6
 1239.0 85
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-6
 3049.0 81
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-6
 8914.0 61
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-6
 4588.0 81
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-6
 8932.0 86
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-6
 14546.0 57
RA1869 Poly(I:C) 2
ug/mL
 3
IL-6
 26287.5 100
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-6
 16087.0 94