Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA1869 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 4382.0 | 53 | |
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 2479.5 | 62 | |
| N2759 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 2183.0 | 59 | |
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 4957.0 | 60 | |
| RA1931 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 7633.5 | 78 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 5097.0 | 48 | |
| N2586 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 7745.0 | 63 | |
| RA1869 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 23346.0 | 66 | |
| RA1869 | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 29220.0 | 47 | ||||
| N2759 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 25570.0 | 54 | |
| N2759 | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 28033.5 | 60 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 23243.0 | 83 | |
| RA1931 | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 29721.0 | 57 | ||||
| N2586 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 29094.0 | 68 | |
| N2586 | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 31820.0 | 67 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-6 | 1587.5 | 64 | ||||
| RA1869 | IKK16 | 2.0 | uM | 1 | IL-6 | 2438.0 | 57 | ||||
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-6 | 3061.0 | 61 | ||||
| N2759 | IKK16 | 2.0 | uM | 1 | IL-6 | 1485.0 | 55 | ||||
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-6 | 3583.0 | 75 | ||||
| RA1931 | IKK16 | 2.0 | uM | 1 | IL-6 | 3922.0 | 56 | ||||
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-6 | 5300.5 | 72 | ||||
| N2586 | IKK16 | 2.0 | uM | 1 | IL-6 | 5035.0 | 65 | ||||
| RA1869 | Tofacitinib | 0.3 | uM | 1 | IL-6 | 3790.0 | 59 | ||||
| RA1869 | 1 | IL-6 | 3035.0 | 77 |