Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
FGF Basic
 384.0 67
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
FGF Basic
 169.5 62
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
FGF Basic
 157.0 55
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
FGF Basic
 1232.5 64
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
FGF Basic
 436.5 66
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
FGF Basic
 206.0 50
RA1869 TNF-a 100
ng/mL
 1
FGF Basic
 206.0 71
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
FGF Basic
 156.0 67
N2759 TNF-a 100
ng/mL
 1
FGF Basic
 188.0 67
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
FGF Basic
 197.5 56
RA1931 TNF-a 100
ng/mL
 1
FGF Basic
 207.0 61
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
FGF Basic
 173.5 60
N2586 TNF-a 100
ng/mL
 1
FGF Basic
 163.0 55
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
FGF Basic
 53.0 62
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
FGF Basic
 51.5 52
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
FGF Basic
 47.0 58
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
FGF Basic
 58.0 59
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
FGF Basic
 44.5 68
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
FGF Basic
 57.5 54
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
FGF Basic
 43.0 46
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
FGF Basic
 52.0 67
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
FGF Basic
 113.0 73
RA1869 IL-1 alpha 100
ng/mL
 1
FGF Basic
 119.0 57
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
FGF Basic
 93.0 71
N2759 IL-1 alpha 100
ng/mL
 1
FGF Basic
 107.0 52