Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
1
Eotaxin
52.5 52
RA1869 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
Eotaxin
53.5 52
N2759 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
1
Eotaxin
68.0 58
N2759 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
Eotaxin
62.0 51
RA1931 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
1
Eotaxin
54.0 50
RA1931 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
Eotaxin
71.5 58
N2586 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
1
Eotaxin
57.0 56
N2586 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
Eotaxin
73.5 50
RA1869 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
1
Eotaxin
123.0 51
RA1869 IL-1 alpha 100
ng/mL
1
Eotaxin
130.0 55
N2759 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
1
Eotaxin
94.0 50
N2759 IL-1 alpha 100
ng/mL
1
Eotaxin
107.0 41
RA1931 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
1
Eotaxin
123.0 50
RA1931 IL-1 alpha 100
ng/mL
1
Eotaxin
115.0 48
N2586 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
1
Eotaxin
125.0 50
N2586 IL-1 alpha 100
ng/mL
1
Eotaxin
103.0 59
RA1869 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
1
Eotaxin
54.0 51
RA1869 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
1
Eotaxin
57.0 49
N2759 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
1
Eotaxin
56.0 59
N2759 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
1
Eotaxin
62.0 53
RA1931 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
1
Eotaxin
56.0 61
RA1931 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
1
Eotaxin
56.5 64
N2586 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
1
Eotaxin
57.0 36
N2586 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
1
Eotaxin
49.5 54
RA1869 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
1
Eotaxin
74.0 51