Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-1B
 320.5 78
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-1B
 356.5 86
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-1B
 278.0 75
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-1B
 347.0 71
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-1B
 324.0 90
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-1B
 359.0 83
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-1B
 314.5 68
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-1B
 341.0 93
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1B
 339.5 82
RA1869 TNF-a 100
ng/mL
 3
IL-1B
 392.0 73
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1B
 352.0 79
N2759 TNF-a 100
ng/mL
 3
IL-1B
 352.0 79
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1B
 381.0 75
RA1931 TNF-a 100
ng/mL
 3
IL-1B
 385.0 79
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1B
 381.0 70
N2586 TNF-a 100
ng/mL
 3
IL-1B
 381.0 77
RA1869 5z-7-oxozeaenol 0.6
uM
 3
IL-1B
 57.0 57
RA1869 IKK16 2.0
uM
 3
IL-1B
 13.0 60
N2759 5z-7-oxozeaenol 0.6
uM
 3
IL-1B
 12.0 65
N2759 IKK16 2.0
uM
 3
IL-1B
 13.0 83
RA1931 5z-7-oxozeaenol 0.6
uM
 3
IL-1B
 14.0 83
RA1931 IKK16 2.0
uM
 3
IL-1B
 13.0 61
N2586 5z-7-oxozeaenol 0.6
uM
 3
IL-1B
 15.0 79
N2586 IKK16 2.0
uM
 3
IL-1B
 16.0 81
RA1869 Tofacitinib 0.3
uM
 3
IL-1B
 15.0 68