Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-2
 53.0 80
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-2
 52.0 60
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-2
 49.0 57
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-2
 55.5 50
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-2
 82.0 55
RA1869 IL-1 alpha 100
ng/mL
 3
IL-2
 83.0 64
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-2
 91.0 43
N2759 IL-1 alpha 100
ng/mL
 3
IL-2
 89.0 61
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-2
 92.0 56
RA1931 IL-1 alpha 100
ng/mL
 3
IL-2
 81.5 58
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-2
 85.0 50
N2586 IL-1 alpha 100
ng/mL
 3
IL-2
 78.5 50
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-2
 87.0 29
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-2
 87.0 55
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-2
 62.0 29
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-2
 87.5 56
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-2
 76.0 62
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-2
 81.5 60
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-2
 73.0 51
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-2
 95.0 53
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-2
 107.0 59
RA1869 TNF-a 100
ng/mL
 3
IL-2
 111.0 48
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-2
 91.0 57
N2759 TNF-a 100
ng/mL
 3
IL-2
 97.5 52
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-2
 100.0 55