Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 20.5 60
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 28.5 52
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 25.0 62
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 37.0 59
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 24.0 50
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 30.0 64
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 83.0 68
RA1869 IL-1 alpha 100
ng/mL
 1
TNF-a
 94.0 49
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 84.0 71
N2759 IL-1 alpha 100
ng/mL
 1
TNF-a
 106.0 67
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 101.0 37
RA1931 IL-1 alpha 100
ng/mL
 1
TNF-a
 87.5 60
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 93.0 56
N2586 IL-1 alpha 100
ng/mL
 1
TNF-a
 94.0 63
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 20.0 46
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 27.0 68
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 23.0 59
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 22.0 42
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 23.0 53
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 24.5 62
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 19.0 44
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 28.0 68
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 49.5 46
RA1869 Poly(I:C) 2
ug/mL
 1
TNF-a
 66.0 50
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 66.0 67