Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
N2586 | 3 | MMP-3 | 355.0 | 39 | |||||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 3 | MMP-3 | 846.5 | 42 | |
RA1869 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 3 | MMP-3 | 377.0 | 41 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 3 | MMP-3 | 117.0 | 59 | |
N2759 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 3 | MMP-3 | 140.0 | 43 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 3 | MMP-3 | 399.0 | 39 | |
RA1931 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 3 | MMP-3 | 474.0 | 52 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 3 | MMP-3 | 434.0 | 27 | |
N2586 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 3 | MMP-3 | 334.0 | 31 | |
RA1869 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 3 | MMP-3 | 502.5 | 36 | |
RA1869 | Poly(I:C) | 2 | ug/mL | 3 | MMP-3 | 772.5 | 22 | ||||
N2759 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 3 | MMP-3 | 698.5 | 38 | |
N2759 | Poly(I:C) | 2 | ug/mL | 3 | MMP-3 | 779.0 | 36 | ||||
RA1931 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 3 | MMP-3 | 367.0 | 25 | |
RA1931 | Poly(I:C) | 2 | ug/mL | 3 | MMP-3 | 408.0 | 24 | ||||
N2586 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 3 | MMP-3 | 1719.0 | 67 | |
N2586 | Poly(I:C) | 2 | ug/mL | 3 | MMP-3 | 1510.0 | 51 | ||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | MMP-3 | 493.0 | 57 | |
RA1869 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | MMP-3 | 2321.5 | 42 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | MMP-3 | 117.0 | 61 | |
N2759 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | MMP-3 | 842.0 | 46 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | MMP-3 | 342.0 | 47 | |
RA1931 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | MMP-3 | 884.5 | 54 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | MMP-3 | 174.0 | 49 | |
N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | MMP-3 | 658.0 | 42 |