Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IL-1 alpha 100
ng/mL
 2
MMP-3
 5101.5 52
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MMP-3
 1251.5 54
N2645 IL-1 alpha 100
ng/mL
 2
MMP-3
 1630.0 53
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MMP-3
 31725.0 34
RA2708 IL-1 alpha 100
ng/mL
 2
MMP-3
 33556.0 44
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MMP-3
 87.0 57
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MMP-3
 113.0 33
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MMP-3
 38.5 48
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MMP-3
 40.0 37
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MMP-3
 546.0 54
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MMP-3
 905.0 41
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
MMP-3
 176.5 46
RA2159 Poly(I:C) 2
ug/mL
 2
MMP-3
 469.0 29
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
MMP-3
 54.5 46
N2645 Poly(I:C) 2
ug/mL
 2
MMP-3
 64.0 36
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
MMP-3
 2625.0 47
RA2708 Poly(I:C) 2
ug/mL
 2
MMP-3
 2551.0 36
RA2159 5z-7-oxozeaenol 0.6
uM
 2
MMP-3
 78.0 48
RA2159 IKK16 2.0
uM
 2
MMP-3
 101.0 49
N2645 5z-7-oxozeaenol 0.6
uM
 2
MMP-3
 36.0 48
N2645 IKK16 2.0
uM
 2
MMP-3
 43.0 53
RA2708 5z-7-oxozeaenol 0.6
uM
 2
MMP-3
 2458.0 54
RA2708 IKK16 2.0
uM
 2
MMP-3
 639.0 63
RA2159 Tofacitinib 0.3
uM
 2
MMP-3
 114.0 48
RA2159 2
MMP-3
 101.0 51