Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | MMP-3 | 1358.0 | 52 | |
| N2586 | Poly(I:C) | 2 | ug/mL | 1 | MMP-3 | 1605.5 | 42 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | 1 | MMP-3 | 371.0 | 16 | ||||
| RA1869 | IKK16 | 2.0 | uM | 1 | MMP-3 | 461.0 | 24 | ||||
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | 1 | MMP-3 | 610.0 | 19 | ||||
| N2759 | IKK16 | 2.0 | uM | 1 | MMP-3 | 159.0 | 32 | ||||
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | 1 | MMP-3 | 340.5 | 34 | ||||
| RA1931 | IKK16 | 2.0 | uM | 1 | MMP-3 | 447.5 | 24 | ||||
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | 1 | MMP-3 | 287.0 | 29 | ||||
| N2586 | IKK16 | 2.0 | uM | 1 | MMP-3 | 280.0 | 49 | ||||
| RA1869 | Tofacitinib | 0.3 | uM | 1 | MMP-3 | 554.0 | 21 | ||||
| RA1869 | 1 | MMP-3 | 526.5 | 44 | |||||||
| N2759 | Tofacitinib | 0.3 | uM | 1 | MMP-3 | 188.5 | 22 | ||||
| N2759 | 1 | MMP-3 | 190.0 | 29 | |||||||
| RA1931 | Tofacitinib | 0.3 | uM | 1 | MMP-3 | 245.5 | 36 | ||||
| RA1931 | 1 | MMP-3 | 359.0 | 22 | |||||||
| N2586 | Tofacitinib | 0.3 | uM | 1 | MMP-3 | 388.5 | 22 | ||||
| N2586 | 1 | MMP-3 | 237.5 | 30 | |||||||
| 0 | MMP-3 | 29.0 | 43 | ||||||||
| 0 | MMP-3 | 20.5 | 40 | ||||||||
| 0 | MMP-3 | 27.0 | 54 | ||||||||
| 0 | MMP-3 | 41.0 | 49 | ||||||||
| 0 | MMP-3 | 37.5 | 16 | ||||||||
| 0 | MMP-3 | 42.0 | 45 | ||||||||
| RA2159 | 2 | MMP-3 | 100.5 | 62 |