Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 TNF-a 100
ng/mL
 2
MMP-2
 232.5 24
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MMP-2
 64.5 44
N2645 TNF-a 100
ng/mL
 2
MMP-2
 63.0 50
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MMP-2
 349.5 22
RA2708 TNF-a 100
ng/mL
 2
MMP-2
 328.0 28
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MMP-2
 192.0 21
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MMP-2
 254.0 36
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MMP-2
 55.5 54
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MMP-2
 65.0 49
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MMP-2
 303.5 40
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MMP-2
 308.5 50
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MMP-2
 286.0 30
RA2159 IL-1 alpha 100
ng/mL
 2
MMP-2
 260.0 41
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MMP-2
 60.0 41
N2645 IL-1 alpha 100
ng/mL
 2
MMP-2
 63.0 39
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MMP-2
 432.0 31
RA2708 IL-1 alpha 100
ng/mL
 2
MMP-2
 322.5 26
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MMP-2
 217.0 33
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MMP-2
 341.0 31
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MMP-2
 65.5 30
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MMP-2
 57.0 45
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MMP-2
 300.0 31
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MMP-2
 353.0 46
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
MMP-2
 178.0 40
RA2159 Poly(I:C) 2
ug/mL
 2
MMP-2
 309.0 25