Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
G-CSF
 44.5 64
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
G-CSF
 42.0 62
N2645 5z-7-oxozeaenol 0.6
uM
 4
G-CSF
 22.0 39
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
G-CSF
 51.5 56
N2759 TNF-a 100
ng/mL
 3
G-CSF
 52.0 75
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
G-CSF
 50.0 81
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
G-CSF
 67.0 52
RA1931 TNF-a 100
ng/mL
 3
G-CSF
 67.0 48
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
G-CSF
 41.5 36
N2586 TNF-a 100
ng/mL
 3
G-CSF
 62.0 69
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
G-CSF
 51.0 51
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
G-CSF
 52.0 73
RA1869 TNF-a 100
ng/mL
 1
G-CSF
 75.0 64
RA1931 5z-7-oxozeaenol 0.6
uM
 3
G-CSF
 17.0 63
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
G-CSF
 47.0 51
N2586 IKK16 2.0
uM
 3
G-CSF
 19.0 71
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
G-CSF
 48.0 64
RA1869 3
G-CSF
 17.5 48
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
G-CSF
 46.0 68
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
G-CSF
 44.0 68
N2586 3
G-CSF
 17.0 66
N2586 Tofacitinib 0.3
uM
 3
G-CSF
 18.0 65
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
G-CSF
 47.5 50
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
G-CSF
 56.0 55
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
G-CSF
 48.5 54