Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 Tofacitinib 0.3
uM
 4
SCF
 56.5 44
RA2708 4
SCF
 54.0 56
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
SCF
 66.0 69
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
SCF
 64.0 67
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
SCF
 53.0 78
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
SCF
 50.5 78
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
SCF
 53.0 69
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
SCF
 47.5 58
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
SCF
 69.0 64
RA2159 Poly(I:C) 2
ug/mL
 4
SCF
 61.0 61
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
SCF
 48.0 52
N2645 Poly(I:C) 2
ug/mL
 4
SCF
 47.0 60
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
SCF
 49.0 67
RA2708 Poly(I:C) 2
ug/mL
 4
SCF
 50.5 56
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
SCF
 71.5 58
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
SCF
 80.0 50
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
SCF
 53.0 54
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
SCF
 60.5 64
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
SCF
 53.0 77
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
SCF
 59.0 56
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
SCF
 79.0 58
RA2159 IL-1 alpha 100
ng/mL
 4
SCF
 71.5 50
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
SCF
 63.0 53
N2645 IL-1 alpha 100
ng/mL
 4
SCF
 58.0 55
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
SCF
 55.0 47