Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
SCF
 42.0 73
RA1869 TNF-a 100
ng/mL
 3
SCF
 38.5 50
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
SCF
 34.5 68
N2759 TNF-a 100
ng/mL
 3
SCF
 32.0 60
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
SCF
 46.0 49
RA1931 TNF-a 100
ng/mL
 3
SCF
 56.5 48
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
SCF
 37.0 52
N2586 TNF-a 100
ng/mL
 3
SCF
 35.0 59
RA1869 5z-7-oxozeaenol 0.6
uM
 3
SCF
 38.0 53
RA1869 IKK16 2.0
uM
 3
SCF
 37.0 71
N2759 5z-7-oxozeaenol 0.6
uM
 3
SCF
 36.5 48
N2759 IKK16 2.0
uM
 3
SCF
 31.0 69
RA1931 5z-7-oxozeaenol 0.6
uM
 3
SCF
 39.0 63
RA1931 IKK16 2.0
uM
 3
SCF
 41.0 66
N2586 5z-7-oxozeaenol 0.6
uM
 3
SCF
 31.5 70
N2586 IKK16 2.0
uM
 3
SCF
 31.5 46
RA1869 Tofacitinib 0.3
uM
 3
SCF
 38.0 47
RA1869 3
SCF
 34.0 51
N2759 Tofacitinib 0.3
uM
 3
SCF
 32.5 58
N2759 3
SCF
 31.5 60
RA1931 Tofacitinib 0.3
uM
 3
SCF
 44.5 48
RA1931 3
SCF
 49.5 48
N2586 Tofacitinib 0.3
uM
 3
SCF
 30.0 45
N2586 3
SCF
 29.0 47
RA1869 3
SCF
 49.0 45