Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
SCF
 51.0 59
RA1931 TNF-a 100
ng/mL
 1
SCF
 61.0 73
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
SCF
 47.5 40
N2586 TNF-a 100
ng/mL
 1
SCF
 39.0 41
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
SCF
 49.0 43
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
SCF
 50.0 60
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
SCF
 39.0 67
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
SCF
 40.0 62
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
SCF
 48.5 58
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
SCF
 54.5 64
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
SCF
 41.0 55
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
SCF
 39.0 53
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
SCF
 45.0 47
RA1869 IL-1 alpha 100
ng/mL
 1
SCF
 56.0 57
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
SCF
 44.0 65
N2759 IL-1 alpha 100
ng/mL
 1
SCF
 38.0 56
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
SCF
 85.0 69
RA1931 IL-1 alpha 100
ng/mL
 1
SCF
 57.0 50
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
SCF
 41.0 43
N2586 IL-1 alpha 100
ng/mL
 1
SCF
 49.0 34
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
SCF
 46.0 29
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
SCF
 44.0 57
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
SCF
 33.0 63
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
SCF
 26.0 43
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
SCF
 42.0 69