Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 Tofacitinib 0.3
uM
 2
IL3
 52.0 37
RA2708 2
IL3
 56.0 30
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL3
 53.5 40
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL3
 57.0 57
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL3
 37.0 35
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL3
 46.0 50
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL3
 41.5 46
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL3
 54.0 51
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL3
 52.0 35
RA2159 TNF-a 100
ng/mL
 2
IL3
 47.0 46
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL3
 56.0 39
N2645 TNF-a 100
ng/mL
 2
IL3
 46.5 52
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL3
 63.0 41
RA2708 TNF-a 100
ng/mL
 2
IL3
 69.0 36
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL3
 80.0 32
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL3
 74.0 31
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL3
 73.0 47
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL3
 76.0 46
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL3
 80.5 42
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL3
 74.0 46
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL3
 78.0 50
RA2159 IL-1 alpha 100
ng/mL
 2
IL3
 67.0 37
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL3
 77.0 36
N2645 IL-1 alpha 100
ng/mL
 2
IL3
 91.0 37
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL3
 95.5 38