Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 5z-7-oxozeaenol 0.6
uM
1
IL1-a
158.0 73
RA1931 IKK16 2.0
uM
1
IL1-a
135.5 60
N2586 5z-7-oxozeaenol 0.6
uM
1
IL1-a
197.0 55
N2586 IKK16 2.0
uM
1
IL1-a
174.0 65
RA1869 Tofacitinib 0.3
uM
1
IL1-a
193.0 71
RA1869 1
IL1-a
158.0 57
N2759 Tofacitinib 0.3
uM
1
IL1-a
200.0 63
N2759 1
IL1-a
189.0 73
RA1931 Tofacitinib 0.3
uM
1
IL1-a
480.0 53
RA1931 1
IL1-a
169.0 65
N2586 Tofacitinib 0.3
uM
1
IL1-a
198.0 27
N2586 1
IL1-a
187.5 54
RA1869 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
1
IL1-a
194.5 54
RA1869 IKK16 2.0
uM
TNF-a 100
ng/mL
1
IL1-a
168.5 64
N2759 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
1
IL1-a
174.5 82
N2759 IKK16 2.0
uM
TNF-a 100
ng/mL
1
IL1-a
196.0 68
RA1931 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
1
IL1-a
1029.5 60
RA1931 IKK16 2.0
uM
TNF-a 100
ng/mL
1
IL1-a
212.0 69
N2586 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
1
IL1-a
156.0 44
N2586 IKK16 2.0
uM
TNF-a 100
ng/mL
1
IL1-a
195.0 61
RA1869 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
IL1-a
183.0 63
RA1869 TNF-a 100
ng/mL
1
IL1-a
215.5 44
N2759 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
IL1-a
179.0 64
N2759 TNF-a 100
ng/mL
1
IL1-a
611.0 61
RA1931 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
IL1-a
2031.0 69