Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
HGF
 69.0 51
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
HGF
 43.0 51
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
HGF
 24.0 50
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
HGF
 21.0 61
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
HGF
 25.0 46
RA1869 Poly(I:C) 2
ug/mL
 3
HGF
 30.0 63
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
HGF
 43.0 65
N2759 Poly(I:C) 2
ug/mL
 3
HGF
 27.0 57
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
HGF
 33.0 44
RA1931 Poly(I:C) 2
ug/mL
 3
HGF
 39.0 55
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
HGF
 23.5 54
N2586 Poly(I:C) 2
ug/mL
 3
HGF
 22.0 59
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 51.0 49
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 40.0 70
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 45.0 50
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 48.0 61
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 68.0 65
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 62.5 58
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 42.5 58
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 37.5 56
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 48.5 58
RA1869 IL-1 alpha 100
ng/mL
 3
HGF
 50.0 57
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 57.0 56
N2759 IL-1 alpha 100
ng/mL
 3
HGF
 62.0 43
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 90.0 57