Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 5z-7-oxozeaenol 0.6
uM
4
b-NGF
39.0 75
RA2159 IKK16 2.0
uM
4
b-NGF
33.0 56
N2645 5z-7-oxozeaenol 0.6
uM
4
b-NGF
204.0 49
N2645 IKK16 2.0
uM
4
b-NGF
204.0 61
RA2708 5z-7-oxozeaenol 0.6
uM
4
b-NGF
44.0 70
RA2708 IKK16 2.0
uM
4
b-NGF
31.0 53
RA2159 Tofacitinib 0.3
uM
4
b-NGF
38.0 49
RA2159 4
b-NGF
38.5 58
N2645 Tofacitinib 0.3
uM
4
b-NGF
247.5 40
N2645 4
b-NGF
320.0 55
RA2708 Tofacitinib 0.3
uM
4
b-NGF
44.5 42
RA2708 4
b-NGF
33.0 55
RA2159 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
4
b-NGF
48.0 41
RA2159 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
4
b-NGF
38.0 55
N2645 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
4
b-NGF
217.0 77
N2645 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
4
b-NGF
229.0 71
RA2708 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
4
b-NGF
49.0 80
RA2708 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
4
b-NGF
38.0 72
RA2159 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
4
b-NGF
64.5 64
RA2159 Poly(I:C) 2
ug/mL
4
b-NGF
76.0 71
N2645 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
4
b-NGF
332.0 59
N2645 Poly(I:C) 2
ug/mL
4
b-NGF
268.0 69
RA2708 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
4
b-NGF
57.5 58
RA2708 Poly(I:C) 2
ug/mL
4
b-NGF
69.0 49
RA2159 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
4
b-NGF
54.0 66