Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-1RA
 94.0 31
RA2159 IL-1 alpha 100
ng/mL
 4
IL-1RA
 100.0 20
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-1RA
 61.0 27
N2645 IL-1 alpha 100
ng/mL
 4
IL-1RA
 62.0 31
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-1RA
 93.0 21
RA2708 IL-1 alpha 100
ng/mL
 4
IL-1RA
 81.5 36
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 101.5 36
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 118.0 39
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 64.0 31
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 95.5 28
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 115.0 29
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 81.0 31
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 121.0 37
RA2159 TNF-a 100
ng/mL
 4
IL-1RA
 144.5 24
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 127.0 25
N2645 TNF-a 100
ng/mL
 4
IL-1RA
 121.0 17
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 104.5 30
RA2708 TNF-a 100
ng/mL
 4
IL-1RA
 81.0 35
RA2159 5z-7-oxozeaenol 0.6
uM
 4
IL-1RA
 28.0 28
RA2159 IKK16 2.0
uM
 4
IL-1RA
 26.5 32
N2645 5z-7-oxozeaenol 0.6
uM
 4
IL-1RA
 26.5 26
N2645 IKK16 2.0
uM
 4
IL-1RA
 18.0 34
RA2708 5z-7-oxozeaenol 0.6
uM
 4
IL-1RA
 28.0 22
RA2708 IKK16 2.0
uM
 4
IL-1RA
 26.0 38
RA2159 Tofacitinib 0.3
uM
 4
IL-1RA
 25.0 22